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Development and characterization of a snapshot Mueller matrix polarimeter for the determination of cervical cancer risk in the low resource setting
Author(s): Jessica C. Ramella-Roman; Mariacarla Gonzalez; Joseph Chue-Sang ; Karla Montejo; Karl Krup; Vijaya Srinivas; Edward DeHoog; Purnima Madhivanan
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Paper Abstract

Mueller Matrix polarimetry can provide useful information about the function and structure of the extracellular matrix. Mueller Matrix systems are sophisticated and costly optical tools that have been used primarily in the laboratory or in hospital settings. Here we introduce a low-cost snapshot Mueller Matrix polarimeter that that does not require external power, has no moving parts, and can acquire a full Mueller Matrix in less than 50 milliseconds. We utilized this technology in the study of cervical cancer in Mysore India, yet the system could be translated in multiple diagnostic applications.

Paper Details

Date Published: 5 April 2018
PDF: 12 pages
Proc. SPIE 10485, Optics and Biophotonics in Low-Resource Settings IV, 104850X (5 April 2018); doi: 10.1117/12.2290592
Show Author Affiliations
Jessica C. Ramella-Roman, Florida International Univ. (United States)
Mariacarla Gonzalez, Florida International Univ. (United States)
Joseph Chue-Sang , Florida International Univ. (United States)
Karla Montejo, Florida International Univ. (United States)
Karl Krup, Public Health Institute of India (India)
Florida International Univ. (United States)
Vijaya Srinivas, Public Health Institute of India (India)
Edward DeHoog, Optical Engineering & Analysis LLC (United States)
Purnima Madhivanan, Public Health Institute of India (India)
Florida International Univ. (United States)

Published in SPIE Proceedings Vol. 10485:
Optics and Biophotonics in Low-Resource Settings IV
David Levitz; Aydogan Ozcan; David Erickson, Editor(s)

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