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Creation of an optically tunable, solid tissue phantom for use in cancer detection
Author(s): Matthew B. Tucker; Catherine Wallace; Sreekar Mantena; Neil Cornwell; Weston Ross; Ren Odion; Tuan Vo-Dinh; Patrick Codd
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Paper Abstract

An optically tunable, solid tissue phantom was developed in order to aid in the verification and validation of non-destructive cancer detection technologies based on fluorescence spectroscopy. The solid tissue phantom contained agarose, hemoglobin, Intralipid, NADH, and FAD. The redox ratio of the solid phantoms were shown to be tunable; thus, indicating that these phantoms could be used to tailor specific optical conditions that mimic cancerous and healthy tissues. Therefore, this solid tissue phantom can serve as a suitable test bed to evaluate fluorescence spectroscopy based cancer detection devices.

Paper Details

Date Published: 8 February 2018
PDF: 9 pages
Proc. SPIE 10480, Clinical and Translational Neurophotonics 2018, 104800H (8 February 2018); doi: 10.1117/12.2290499
Show Author Affiliations
Matthew B. Tucker, Duke Univ. (United States)
Catherine Wallace, Medical College of Georgia (United States)
Sreekar Mantena, North Carolina School of Science and Mathematics (United States)
Neil Cornwell, North Carolina State Univ. (United States)
Weston Ross, Duke Univ. (United States)
Ren Odion, Duke Univ. (United States)
Tuan Vo-Dinh, Duke Univ. (United States)
Patrick Codd, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 10480:
Clinical and Translational Neurophotonics 2018
Steen J. Madsen; Victor X. D. Yang, Editor(s)

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