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Proceedings Paper

Integrated sensor biopsy device for real time tissue metabolism analysis
Author(s): Jesus Delgado Alonso ; Robert A. Lieberman; Paul M. DiCarmine; David Berry; Narciso Guzman; Sreekar B. Marpu
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Paper Abstract

Current methods for guiding cancer biopsies rely almost exclusively on images derived from X-ray, ultrasound, or magnetic resonance, which essentially characterize suspected lesions based only on tissue density. This paper presents a sensor integrated biopsy device for in situ tissue analysis that will enable biopsy teams to measure local tissue chemistry in real time during biopsy procedures, adding a valuable new set of parameters to augment and extend conventional image guidance. A first demonstrator integrating three chemical and biochemical sensors was tested in a mice strain that is a spontaneous breast cancer model. In all cases, the multisensory probe was able to discriminate between healthy tissue, the edge of the tumor, and total insertion inside the cancer tissue, recording real-time information about tissue metabolism.

Paper Details

Date Published: 13 February 2018
PDF: 8 pages
Proc. SPIE 10488, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, 104880P (13 February 2018); doi: 10.1117/12.2290323
Show Author Affiliations
Jesus Delgado Alonso , Intelligent Optical Systems, Inc. (United States)
Robert A. Lieberman, Lumoptix, LLC (United States)
Paul M. DiCarmine, Intelligent Optical Systems, Inc. (United States)
David Berry, Intelligent Optical Systems, Inc. (United States)
Narciso Guzman, Intelligent Optical Systems, Inc. (United States)
Sreekar B. Marpu, Univ. of North Texas (United States)


Published in SPIE Proceedings Vol. 10488:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
Israel Gannot, Editor(s)

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