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Proceedings Paper

Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances
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Paper Abstract

Laser Doppler flowmetry (LDF) is widely used to study blood microcirculation in the skin. However, during tradition signal processing based on the integral estimations of the power spectrum of detector photocurrent, the significant part of the information about the skin blood ow is lost. In this study, we propose to analyse the distribution of the blood perfusion over the Doppler shift frequencies, which correlate with the RBC velocity. This approach provides localisation of the blood ow oscillations in different subranges of the Doppler shift. The method applied together with the wavelet analysis has been tested in healthy volunteers and patients with psoriasis on the unaffected surface of the skin. It was revealed, that the significant difference in the amplitude of myogenic oscillations is allocated in the region of the low frequency Doppler shift (1-200 Hz). This frequency region can be associated with the signal from slow components of the skin microcirculation, that can point out on a different state of the lymphatic system of the skin in psoriasis.

Paper Details

Date Published: 17 May 2018
PDF: 4 pages
Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 106854O (17 May 2018); doi: 10.1117/12.2289551
Show Author Affiliations
Igor O. Kozlov, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Evgeny A. Zherebtsov, Aston Univ. (United Kingdom)
Victor V. Dremin, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Angelina I. Zherebtsova, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Elena V. Zharkikh, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Andrey V. Dunaev, Orel State Univ. named after I.S. Turgenev (Russian Federation)
Edik U. Rafailov, Aston Univ. (United Kingdom)


Published in SPIE Proceedings Vol. 10685:
Biophotonics: Photonic Solutions for Better Health Care VI
Jürgen Popp; Valery V. Tuchin; Francesco Saverio Pavone, Editor(s)

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