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Proceedings Paper

Four-dimensional optoacoustic temperature mapping in laser-induced thermotherapy
Author(s): Francisco Javier Oyaga Landa; Xosé Luís Deán-Ben; Ronald Sroka; Daniel Razansky
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Paper Abstract

Photoablative laser therapy is in common use for selective destruction of malignant masses, vascular and brain abnormalities. Tissue ablation and coagulation are irreversible processes occurring shortly after crossing a certain thermal exposure threshold. As a result, accurate mapping of the temperature field is essential for optimizing the outcome of these clinical interventions. Here we demonstrate four-dimensional optoacoustic temperature mapping of the entire photoablated region. Accuracy of the method is investigated in tissue-mimicking phantom experiments. Deviations of the volumetric optoacoustic temperature readings provided at 40ms intervals remained below 10% for temperature elevations above 3°C, as validated by simultaneous thermocouple measurements. The excellent spatio-temporal resolution of the new temperature monitoring approach aims at improving safety and efficacy of laser-based photothermal procedures.

Paper Details

Date Published: 19 February 2018
PDF: 5 pages
Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104940D (19 February 2018); doi: 10.1117/12.2288924
Show Author Affiliations
Francisco Javier Oyaga Landa, Helmholtz Zentrum München GmbH (Germany)
Technische Univ. München (Germany)
Xosé Luís Deán-Ben, Helmholtz Zentrum München GmbH (Germany)
Ronald Sroka, Ludwig-Maximilian-Univ. (Germany)
Daniel Razansky, Helmholtz Zentrum München GmbH (Germany)
Technische Univ. München (Germany)

Published in SPIE Proceedings Vol. 10494:
Photons Plus Ultrasound: Imaging and Sensing 2018
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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