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Monte Carlo simulation of near-infrared light propagation in realistic adult head models with hair follicles
Author(s): Boan Pan; Xiang Fang; Weichao Liu; Nanxi Li; Ke Zhao; Ting Li
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Paper Abstract

Near infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS) has been used to measure brain activation, which are clinically important. Monte Carlo simulation has been applied to the near infrared light propagation model in biological tissue, and has the function of predicting diffusion and brain activation. However, previous studies have rarely considered hair and hair follicles as a contributing factor. Here, we attempt to use MCVM (Monte Carlo simulation based on 3D voxelized media) to examine light transmission, absorption, fluence, spatial sensitivity distribution (SSD) and brain activation judgement in the presence or absence of the hair follicles. The data in this study is a series of high-resolution cryosectional color photograph of a standing Chinse male adult. We found that the number of photons transmitted under the scalp decreases dramatically and the photons exported to detector is also decreasing, as the density of hair follicles increases. If there is no hair follicle, the above data increase and has the maximum value. Meanwhile, the light distribution and brain activation have a stable change along with the change of hair follicles density. The findings indicated hair follicles make influence of NIRS in light distribution and brain activation judgement.

Paper Details

Date Published: 12 February 2018
PDF: 6 pages
Proc. SPIE 10484, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVI, 1048414 (12 February 2018); doi: 10.1117/12.2288730
Show Author Affiliations
Boan Pan, Univ. of Electronic Science and Technology of China (China)
Peking Union Medical College (China)
Xiang Fang, Peking Union Medical College (China)
Weichao Liu, Peking Union Medical College (China)
Nanxi Li, Univ. of Electronic Science and Technology of China (China)
Peking Union Medical College (China)
Ke Zhao, Univ. of Electronic Science and Technology of China (China)
Peking Union Medical College (China)
Ting Li, Peking Union Medical College (China)


Published in SPIE Proceedings Vol. 10484:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVI
Tuan Vo-Dinh; Anita Mahadevan-Jansen; Warren S. Grundfest, Editor(s)

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