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Proceedings Paper

Noninvasive monitoring local variations of fever and edema on human: potential for point-of-care inflammation assessment
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Paper Abstract

Tissue inflammation is often accompanied by fever and edema, which are common and troublesome problems that probably trigger disability, lymphangitis, cosmetic deformity and cellulitis. Here we developed a device, which can measure concentration and temperature variations of water in local human body by extended near infrared spectroscopy in 900~1000 nm wavelength range. An experiment of four steps incremental cycling exercise was designed to change tissue water concentration and temperature of subjects. Body temperature was also estimated by tympanic thermometer and surface thermometer as comparisons during the experiment. In the stage of recovery after exercise, the signal detected by custom device is similar to tympanic thermometer at the beginning, but it is closer to the temperature of surface later. In particular, this signal shows a better linearity, and a significant change when the exercise was suspended. This study demonstrated the potential of optical touch-sensing for inflammation severity monitoring by measuring water concentration and temperature variations in local lesions.

Paper Details

Date Published: 8 February 2018
PDF: 7 pages
Proc. SPIE 10479, Light-Based Diagnosis and Treatment of Infectious Diseases, 104790D (8 February 2018); doi: 10.1117/12.2288659
Show Author Affiliations
Zebin Li, Univ. of Electronic Science and Technology of China (China)
Xianglin Li, Univ. of Electronic Science and Technology of China (China)
Chinese Academy of Medical Science and Peking Union Medical College (China)
Ting Li, Chinese Academy of Medical Science and Peking Union Medical College (China)


Published in SPIE Proceedings Vol. 10479:
Light-Based Diagnosis and Treatment of Infectious Diseases
Tianhong Dai, Editor(s)

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