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Proceedings Paper

Structural characterization on in vitro porcine skin treated by ablative fractional laser using optical coherence tomography
Author(s): Kairui Feng; Kanheng Zhou; Yuting Ling; Paul O'Mahoney; Eadie Ewan; Sally H. Ibbotson; Chunhui Li; Zhihong Huang
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Paper Abstract

Ablative fractional skin laser is widely applied for various skin conditions, especially for cosmetic repairing and promoting the located drug delivery. Although the influence of laser treatment over the skin has been explored before in means of excision and biopsy with microscopy, these approaches are invasive, only morphological and capable of distorting the skin. In this paper the authors use fresh porcine skin samples irradiated by the lasers, followed by detected by using Optical Coherence Tomography (OCT). This advanced optical technique has the ability to present the high resolution structure image of treated sample. The results shows that laser beams can produce holes left on the surface after the irradiation. The depth of holes can be affected by changes of laser energy while the diameter of holes have no corresponding relation. Plus, OCT, as a valuable imaging technology, is capable of monitoring the clinical therapy procedure and assisting the calibration.

Paper Details

Date Published: 19 February 2018
PDF: 6 pages
Proc. SPIE 10496, Optical Elastography and Tissue Biomechanics V, 104960H (19 February 2018); doi: 10.1117/12.2288492
Show Author Affiliations
Kairui Feng, Univ. of Dundee (United Kingdom)
Kanheng Zhou, Univ. of Dundee (United Kingdom)
Yuting Ling, Univ. of Dundee (United Kingdom)
Paul O'Mahoney, Ninewells Hospital (United Kingdom)
The Scottish Photodynamic Therapy Ctr. (United Kingdom)
Eadie Ewan, Ninewells Hospital (United Kingdom)
The Scottish Photodynamic Therapy Ctr. (United Kingdom)
Sally H. Ibbotson, Ninewells Hospital (United Kingdom)
The Scottish Photodynamic Therapy Ctr. (United Kingdom)
Chunhui Li, Univ. of Dundee (United Kingdom)
Zhihong Huang, Univ. of Dundee (United Kingdom)

Published in SPIE Proceedings Vol. 10496:
Optical Elastography and Tissue Biomechanics V
Kirill V. Larin; David D. Sampson, Editor(s)

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