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In vivo observation of transient photoreceptor movement correlated with oblique light stimulation
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Paper Abstract

Rod-dominated transient retinal phototropism (TRP) has been observed in freshly isolated retinas, promising a noninvasive biomarker for high resolution assessment of retinal physiology. However, in vivo mapping of TRP is challenging due to its fast time course and sub-cellular signal magnitude. By developing a line-scanning and virtually structured detection based super-resolution ophthalmoscope, we report here in vivo observation of TRP in frog retina. In vivo characterization of TRP time course and magnitude were implemented by using variable light stimulus intensities.

Paper Details

Date Published: 20 February 2018
PDF: 6 pages
Proc. SPIE 10497, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI, 104971M (20 February 2018); doi: 10.1117/12.2287262
Show Author Affiliations
Yiming Lu, Univ. of Illinois at Chicago (United States)
Changgeng Liu, Univ. of Illinois at Chicago (United States)
Xincheng Yao, Univ. of Illinois at Chicago (United States)


Published in SPIE Proceedings Vol. 10497:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVI
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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