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In-vitro singlet oxygen threshold dose at PDT with Radachlorin photosensitizer
Author(s): V. V. Klimenko; S. V. Shmakov; N. E. Kaydanov; N. A. Knyazev; N. V. Kazakov; A. A. Rusanov; A. A. Bogdanov; M. V. Dubina
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Paper Abstract

In this present study we investigate the Radachlorin photosensitizer accumulation in K562 cells and Hela cells and determined the cell viability after PDT. Using the macroscopic singlet oxygen modeling and cellular photosensitizer concentration the singlet oxygen threshold doses for K562 cells and Hela cells were calculated.

Paper Details

Date Published: 1 August 2017
PDF: 8 pages
Proc. SPIE 10417, Medical Laser Applications and Laser-Tissue Interactions VIII, 1041703 (1 August 2017); doi: 10.1117/12.2286457
Show Author Affiliations
V. V. Klimenko, St Petersburg Academic Univ. (Russian Federation)
S. V. Shmakov, St Petersburg Academic Univ. (Russian Federation)
N. E. Kaydanov, St Petersburg Academic Univ. (Russian Federation)
N. A. Knyazev, St Petersburg Academic Univ. (Russian Federation)
Institute of Cytology (Russian Federation)
N. V. Kazakov, First Pavlov State Medical Univ. of St Petersburg (Russian Federation)
A. A. Rusanov, First Pavlov State Medical Univ. of St Petersburg (Russian Federation)
A. A. Bogdanov, St Petersburg Academic Univ. (Russian Federation)
St Petersburg State Polytechnical Univ. (Russian Federation)
M. V. Dubina, St Petersburg Academic Univ. (Russian Federation)
St Petersburg State Polytechnical Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10417:
Medical Laser Applications and Laser-Tissue Interactions VIII
Lothar D. Lilge; Ronald Sroka, Editor(s)

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