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Photoacoustic imaging optimization with raw signal deconvolution and empirical mode decomposition
Author(s): Chengwen Guo; Jing Wang; Yu Qin; Hongchen Zhan; Jie Yuan; Qian Cheng; Xueding Wang
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Paper Abstract

Photoacoustic (PA) signal of an ideal optical absorb particle is a single N-shape wave. PA signals of a complicated biological tissue can be considered as the combination of individual N-shape waves. However, the N-shape wave basis not only complicates the subsequent work, but also results in aliasing between adjacent micro-structures, which deteriorates the quality of the final PA images. In this paper, we propose a method to improve PA image quality through signal processing method directly working on raw signals, which including deconvolution and empirical mode decomposition (EMD). During the deconvolution procedure, the raw PA signals are de-convolved with a system dependent point spread function (PSF) which is measured in advance. Then, EMD is adopted to adaptively re-shape the PA signals with two constraints, positive polarity and spectrum consistence. With our proposed method, the built PA images can yield more detail structural information. Micro-structures are clearly separated and revealed. To validate the effectiveness of this method, we present numerical simulations and phantom studies consist of a densely distributed point sources model and a blood vessel model. In the future, our study might hold the potential for clinical PA imaging as it can help to distinguish micro-structures from the optimized images and even measure the size of objects from deconvolved signals.

Paper Details

Date Published: 19 February 2018
PDF: 7 pages
Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 1049451 (19 February 2018); doi: 10.1117/12.2286411
Show Author Affiliations
Chengwen Guo, Nanjing Univ. (China)
Jing Wang, Nanjing Univ. (China)
Yu Qin, Tongji Univ. (China)
Hongchen Zhan, Nanjing Univ. (China)
Jie Yuan, Nanjing Univ. (China)
Qian Cheng, Tongji Univ. (China)
Xueding Wang, Tongji Univ. (China)
Univ. of Michigan (United States)

Published in SPIE Proceedings Vol. 10494:
Photons Plus Ultrasound: Imaging and Sensing 2018
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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