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Light and ultrasound activated microbubbles around gold nanorods for photoacoustic microsurgery
Author(s): Lucia Cavigli; Sonia Centi; Sarah Lai; Claudia Borri; Filippo Micheletti; Paolo Tortoli; Ilaria Panettieri; Ingolf Streit; Francesca Rossi; Fulvio Ratto; Roberto Pini
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Paper Abstract

Photoacoustic imaging and microsurgery have recently attracted attention for applications in oncology. Here, we present a versatile set-up to trigger vapor microbubbles around plasmonic nanoparticles by a combined light-ultrasound excitation. This system enables the detection and parametrization of bubbles as a function of several variables, such us optical fluence, ultrasound intensity, nanoparticles concentration, thus providing useful directions to the development of new strategies for treatments based on optical cavitation.

Paper Details

Date Published: 1 August 2017
PDF: 5 pages
Proc. SPIE 10415, Opto-Acoustic Methods and Applications in Biophotonics III, 1041504 (1 August 2017); doi: 10.1117/12.2286055
Show Author Affiliations
Lucia Cavigli, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Sonia Centi, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Sarah Lai, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Claudia Borri, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Filippo Micheletti, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Paolo Tortoli, Univ. degli Studi di Firenze (Italy)
Ilaria Panettieri, Politecnico di Torino (Italy)
Ingolf Streit, Asclepion Laser Technologies GmbH (Germany)
Francesca Rossi, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Fulvio Ratto, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)
Roberto Pini, Istituto di Fisica Applicata Nello Carrara, CNR (Italy)


Published in SPIE Proceedings Vol. 10415:
Opto-Acoustic Methods and Applications in Biophotonics III
Vasilis Ntziachristos; Roger Zemp, Editor(s)

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