Share Email Print
cover

Proceedings Paper • new

Laser-excited gold nanoparticles for treatment of cancer cells in vitro
Author(s): Noé Zamora-Romero; Vicente Robles; Crysthal Alvarez; Natanael Cuando-Espitia; Luis F. Devia-Cruz; Elias Penilla; David L. Halaney; Guillermo Aguilar
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Several in vitro and in vivo studies have been performed to investigate the potential of Photothermal Therapy (PTT) as a cancer treatment strategy. However, there are still open questions concerning the optimal parameters for generating cavitation bubbles and acoustic shockwaves for increasing the damage to malignant cells, and the primary mechanism for cell damage in PTT is still a matter of debate. This study investigates PTT based on shockwaves from cavitation induced far from the cells, due to laser absorption by gold nanorods (GNR) colloidal solutions in vitro. The effects of laser energy and distance from the cavitation on cell viability is investigated in PC3 prostate cancer cells, and Escherichia coli (E. coli) cells, respectively.

Paper Details

Date Published: 1 August 2017
PDF: 7 pages
Proc. SPIE 10417, Medical Laser Applications and Laser-Tissue Interactions VIII, 1041707 (1 August 2017); doi: 10.1117/12.2286005
Show Author Affiliations
Noé Zamora-Romero, Univ. of California, Riverside (United States)
Vicente Robles, Univ. of California, Riverside (United States)
Crysthal Alvarez, Univ. of California, Riverside (United States)
Natanael Cuando-Espitia, Univ. of California, Riverside (United States)
Luis F. Devia-Cruz, Univ. of California, Riverside (United States)
Elias Penilla, Univ. of California, Riverside (United States)
David L. Halaney, Univ. of California, Riverside (United States)
Guillermo Aguilar, Univ. of California, Riverside (United States)


Published in SPIE Proceedings Vol. 10417:
Medical Laser Applications and Laser-Tissue Interactions VIII
Lothar D. Lilge; Ronald Sroka, Editor(s)

© SPIE. Terms of Use
Back to Top