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Proceedings Paper

A sensor array for detection proteins using lanthanide-doped nanoparticles
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Paper Abstract

Lanthanide (Ln3+)-doped nanoparticles (NPs) have shown great promise in versatile bioassay. We constructed a supramolecular sensor array by hybridized time-resolved Förster resonance energy transfer (TR-FRET) with the indicator displacement assay (IDA) concept. The sensor array was generated by binding a series of negatively charged indicators on the surface of NaYF4:Ce/Tb NPs. The sensor array could successfully discriminate 6 model proteins with high accuracy and sensitivity both qualitatively and quantitatively.

Paper Details

Date Published: 19 February 2018
PDF: 5 pages
Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 104950V (19 February 2018); doi: 10.1117/12.2285921
Show Author Affiliations
Meng Wang, Shenzhen Univ. (China)
Benqing Zhou, Shenzhen Univ. (China)
Feifan Zhou, Shenzhen Univ. (China)
Univ. of Central Oklahoma (United States)
Junle Qu, Shenzhen Univ. (China)
Wei R. Chen, Shenzhen Univ. (China)
Univ. of Central Oklahoma (United States)


Published in SPIE Proceedings Vol. 10495:
Biophotonics and Immune Responses XIII
Wei R. Chen, Editor(s)

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