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Proceedings Paper

Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells
Author(s): Sonja Johannsmeier; Patrick Heeger; Mitsuhiro Terakawa; Stefan Kalies; Alexander Heisterkamp; Tammo Ripken; Dag Heinemann
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Paper Abstract

Gold nanoparticle mediated laser stimulation of neuronal cells allows for cell activation on a single-cell level. It could therefore be considered an alternative to classical electric neurostimulation. The physiological impact of this new approach has not been intensively studied so far. Here, we investigate the targeted cell’s reaction to a laser stimulus based on its calcium response. A complex cellular reaction involving multiple sources has been revealed.

Paper Details

Date Published: 1 August 2017
PDF: 5 pages
Proc. SPIE 10417, Medical Laser Applications and Laser-Tissue Interactions VIII, 104170B (1 August 2017); doi: 10.1117/12.2284174
Show Author Affiliations
Sonja Johannsmeier, Laser Zentrum Hannover e.V. (Germany)
Lower Saxony Ctr. for Biomedical Engineering (Germany)
Patrick Heeger, Hearing4All (Germany)
Gottfried Wilhelm Leibniz Univ. Hannover (Germany)
Lower Saxony Ctr. for Biomedical Engineering (Germany)
Mitsuhiro Terakawa, Keio Univ. (Japan)
Stefan Kalies, Gottfried Wilhelm Leibniz Univ. Hannover (Germany)
Lower Saxony Ctr. for Biomedical Engineering (Germany)
Alexander Heisterkamp, Laser Zentrum Hannover e.V (Germany)
Hearing4All (Germany)
Gottfried Wilhelm Leibniz Univ. Hannover (Germany) and Lower Saxony Ctr. for Biomedical Engineering (Germany)
Tammo Ripken, Laser Zentrum Hannover e.V. (Germany)
Hearing4All (Germany)
Dag Heinemann, Laser Zentrum Hannover e.V. (Germany)
Hearing4All (Germany)
Lower Saxony Ctr. for Biomedical Engineering (Germany)


Published in SPIE Proceedings Vol. 10417:
Medical Laser Applications and Laser-Tissue Interactions VIII
Lothar D. Lilge; Ronald Sroka, Editor(s)

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