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Studies of photosensitizers from the phthalocyanine family in the perspective of two-photon photodynamic therapy
Author(s): Michel Fournier
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Paper Abstract

Photodynamic therapy (PDT) of cancer is a treatment with strengths and weaknesses. Amongst the latter is the need for the presence of oxygen for the photodynamic effect to occur. It is a known fact that singlet oxygen, generated from the first triplet excited state (T1) of the photosensitizer, is responsible for the lethal photodynamic effect [1, 2, 3, 4]. The problem lies in the lack of oxygen in the core of a tumor. It seems that the excited triplet state energy of the photosensitizers currently in use in PDT lies below the threshold of a lethal anoxic chemical reaction.

Paper Details

Date Published: 29 August 2017
PDF: 3 pages
Proc. SPIE 10313, Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging, 1031338 (29 August 2017); doi: 10.1117/12.2283912
Show Author Affiliations
Michel Fournier, Univ. de Sherbrooke (Canada)

Published in SPIE Proceedings Vol. 10313:
Opto-Canada: SPIE Regional Meeting on Optoelectronics, Photonics, and Imaging
John C. Armitage, Editor(s)

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