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Proceedings Paper

The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells
Author(s): Anna V. Tcibulnikova; Igor A. Degterev ; Valery V. Bryukhanov; Matheus Mantuanelli Roberto ; F. D. Campos Pereira; M. A. Marin-Morales; Vasily A. Slezhkin; Ilya G. Samusev
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Paper Abstract

We have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Açaí) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen.

Paper Details

Date Published: 2 January 2018
PDF: 6 pages
Proc. SPIE 10456, Nanophotonics Australasia 2017, 104563E (2 January 2018); doi: 10.1117/12.2283317
Show Author Affiliations
Anna V. Tcibulnikova, Immanuel Kant Baltic Federal Univ. (Russian Federation)
Igor A. Degterev , Immanuel Kant Baltic Federal Univ. (Russian Federation)
Univ. Federal do Acre, Biotecnologia e Biodiversidade (Brazil)
Valery V. Bryukhanov, Immanuel Kant Baltic Federal Univ. (Russian Federation)
Matheus Mantuanelli Roberto , São Paulo State Univ. (Brazil)
Hermínio Ometto Univ. Ctr. (Brazil)
F. D. Campos Pereira, São Paulo State Univ. (Brazil)
Paulista Univ. (Brazil)
M. A. Marin-Morales, São Paulo State Univ. (Brazil)
Vasily A. Slezhkin, Immanuel Kant Baltic Federal Univ. (Russian Federation)
Ilya G. Samusev, Immanuel Kant Baltic Federal Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10456:
Nanophotonics Australasia 2017
James W. M. Chon; Baohua Jia, Editor(s)

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