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Proceedings Paper

Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma
Author(s): Ajeetkumar Patil; Swati Rao K.; Unnikrishnan V. K.; Keerthilatha M. Pai; V. B. Kartha; Santhosh Chidangil
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Paper Abstract

Autofluorescence spectroscopy offer noninvasive and promising tools for the detection of alternations biochemical compositions of tissues and cells, in presence of disease. They have the added advantage of being highly objective due to the fact that diagnostic evaluation is by statistical methods, eliminating errors from lack of experience, fatigue factor, and subjectivity of visual perceptions. The present research work involves in designing and assembling of a low cost, miniature oral cancer screening device with for routine clinical applications. A miniature system was designed and assembled with much smaller and cost-effective components like compact light source and miniature spectrometer, in a hand-held unit configuration. The performance of the system was evaluated using animal -mouse- SCC model. The current system can be used in handheld operation, which makes it very useful for many applications like, screening of squamous cell carcinoma susceptible population.

Paper Details

Date Published: 28 July 2017
PDF: 3 pages
Proc. SPIE 10411, Clinical and Preclinical Optical Diagnostics, 104110V (28 July 2017); doi: 10.1117/12.2282888
Show Author Affiliations
Ajeetkumar Patil, Singapore-MIT Alliance for Research and Technology (India)
Manipal Univ. (India)
Swati Rao K., Manipal Univ. (India)
Unnikrishnan V. K., Manipal Univ. (India)
Keerthilatha M. Pai, Manipal Univ. (India)
V. B. Kartha, Manipal Univ. (India)
Santhosh Chidangil, Manipal Univ. (India)


Published in SPIE Proceedings Vol. 10411:
Clinical and Preclinical Optical Diagnostics
J. Quincy Brown; Ton G. van Leeuwen, Editor(s)

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