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Proceedings Paper

Adaptive optical microscope for brain imaging in vivo
Author(s): Kai Wang
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Paper Abstract

The optical heterogeneity of biological tissue imposes a major limitation to acquire detailed structural and functional information deep in the biological specimens using conventional microscopes. To restore optimal imaging performance, we developed an adaptive optical microscope based on direct wavefront sensing technique. This microscope can reliably measure and correct biological samples induced aberration. We demonstrated its performance and application in structural and functional brain imaging in various animal models, including fruit fly, zebrafish and mouse.

Paper Details

Date Published: 18 April 2017
PDF: 2 pages
Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 102510H (18 April 2017); doi: 10.1117/12.2274950
Show Author Affiliations
Kai Wang, Insitute of Neuroscience (China)
State Key Lab. of Neuroscience (China)
Univ. of Chinese Academy of Sciences (China)


Published in SPIE Proceedings Vol. 10251:
Biomedical Imaging and Sensing Conference
Toyohiko Yatagai; Yoshihisa Aizu; Osamu Matoba; Yasuhiro Awatsuji, Editor(s)

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