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Proceedings Paper

A printed electronic platform for the specific detection of biomolecules
Author(s): A. Doumbia; M. Webb; M. L. Turner; J. M. Behrendt; R. Wilson
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Paper Abstract

The rapid detection of disease specific biomarkers in a clinically relevant range using a low-cost sensor can facilitate the development of individual treatment plans for a given patient, known as precision, personalized or genomic medicine. In the recent decade Electrolyte-Gated Organic Field Effect Transistors (EGOFETs), a subtype of OFETs where the dielectric is replaced by an electrolyte, have attracted a great deal of attention for sensing applications. This is due to their capacity to operate at low voltage (< 1 volt) in physiological like media. Although EGOFET based biosensors have been shown to specifically detect biomolecules with high sensitivity and selectivity; the stability, reproducibility, and performance required to reach the desired market are not yet achieved. In this contribution, we describe the development of a stable and reproducible EGOFET sensor that is able to detect biomolecules selectively in real-time. Facile and scalable techniques are used to prepare arrays of these devices. The selectivity of individual EGOFETs is investigated by immobilization of specific ligands to the target molecule of interest on the gate electrode within a microfluidic flow cell.

Paper Details

Date Published: 25 August 2017
PDF: 10 pages
Proc. SPIE 10364, Organic Sensors and Bioelectronics X, 103640N (25 August 2017); doi: 10.1117/12.2274038
Show Author Affiliations
A. Doumbia, The Univ. of Manchester (United Kingdom)
M. Webb, The Univ. of Manchester (United Kingdom)
M. L. Turner, The Univ. of Manchester (United Kingdom)
J. M. Behrendt, Cambridge Display Technology Ltd. (United Kingdom)
R. Wilson, Cambridge Display Technology Ltd. (United Kingdom)


Published in SPIE Proceedings Vol. 10364:
Organic Sensors and Bioelectronics X
Ioannis Kymissis; Ruth Shinar; Luisa Torsi, Editor(s)

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