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Cellular biophysical markers of hydroxyurea treatment in sickle cell disease
Author(s): Peter T. C. So; Poorya Hosseini; Sabia Z. Abidi; E. Du; Dimitrios P. Papageorgiou; YongKeun Park; John Higgins; Gregory J. Kato; Subra Suresh; Ming Dao; Zahid Yaqoob
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Paper Abstract

Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured parameters.

Paper Details

Date Published: 18 April 2017
PDF: 2 pages
Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 1025103 (18 April 2017); doi: 10.1117/12.2273139
Show Author Affiliations
Peter T. C. So, Massachusetts Institute of Technology (United States)
Poorya Hosseini, Massachusetts Institute of Technology (United States)
Sabia Z. Abidi, Massachusetts Institute of Technology (United States)
E. Du, Florida Atlantic Univ. (United States)
Dimitrios P. Papageorgiou, Massachusetts Institute of Technology (United States)
YongKeun Park, KAIST (Korea, Republic of)
John Higgins, Harvard Medical School (United States)
Gregory J. Kato, Univ. of Pittsburgh (United States)
Subra Suresh, Carnegie Mellon Univ. (United States)
Ming Dao, Massachusetts Institute of Technology (United States)
Zahid Yaqoob, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 10251:
Biomedical Imaging and Sensing Conference
Toyohiko Yatagai; Yoshihisa Aizu; Osamu Matoba; Yasuhiro Awatsuji, Editor(s)

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