Share Email Print
cover

Proceedings Paper

Optical methods in diagnostics of liver fibrosis via blood observation
Author(s): Margarita V. Kruchinina; Vladimir M. Generalov; Victor V. Atuchin; Vladimir N. Kruchinin; Vladimir A. Volodin; Andrey A. Gromov; Sergey V. Rykhlitsky
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

A possible application of optical methods (dielectrophoresis, spectral and imaging ellipsometry, Fourier- transform infrared spectroscopy, Raman spectroscopy) for the early diagnostics in studies of red blood cells and serum in patients with the diffuse liver disease, with varying degrees of fibrosis, has been evaluated. As experimentally confirmed, the combined optical methods significantly improve the sensitivity, specificity and accuracy index in the diagnosis of both severe fibrosis and slight ulterior liver fibrosis. The identified optical methods diagnostic potential can be efficiently utilized in noninvasive screening evaluation of the stages of diffuse liver disease of various genesis.

Paper Details

Date Published: 14 December 2016
PDF: 10 pages
Proc. SPIE 10176, Asia-Pacific Conference on Fundamental Problems of Opto- and Microelectronics, 1017608 (14 December 2016); doi: 10.1117/12.2268136
Show Author Affiliations
Margarita V. Kruchinina, Institution of Internal and Preventive Medicine (Russian Federation)
Vladimir M. Generalov, State Research Ctr. of Virology and Biotechnology VECTOR (Russian Federation)
Victor V. Atuchin, A.V. Rzhanov Institute of Semiconductor Physics (Russian Federation)
Tomsk State Univ. (Russian Federation)
Novosibirsk State Univ. (Russian Federation)
Vladimir N. Kruchinin, A.V. Rzhanov Institute of Semiconductor Physics (Russian Federation)
Vladimir A. Volodin, A.V. Rzhanov Institute of Semiconductor Physics (Russian Federation)
Novosibirsk State Univ. (Russian Federation)
Andrey A. Gromov, Institution of Internal and Preventive Medicine (Russian Federation)
Sergey V. Rykhlitsky, A.V. Rzhanov Institute of Semiconductor Physics (Russian Federation)


Published in SPIE Proceedings Vol. 10176:
Asia-Pacific Conference on Fundamental Problems of Opto- and Microelectronics
Yuri N. Kulchin; Roman V. Romashko; Alexander V. Syuy, Editor(s)

© SPIE. Terms of Use
Back to Top