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Evaluation of blood microcirculation parameters by combined use of laser Doppler flowmetry and videocapillaroscopy methods
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Paper Abstract

Laser Doppler flowmetry (LDF) is widely used for diagnosing blood microcirculation diseases. It is well known that the Doppler shift of laser radiation scattered by moving red blood cells (RBC) can be assessed through analyzing photocurrent produced by a photodetector. LDF signal contains information about regulating blood flow rhythms: myogenic, cardiac, nervous and endothelial. The method of videocapillaroscopy (VCS) allows local capillary blood flow velocity evaluation and, using video data processing algorithms, is able to assess RBC velocity changes into capillary. We present the results of simultaneous investigations of changes in tissue perfusion of the distal phalanx of human finger by the LDF as well as changes in capillary blood flow velocity in the nail bed evaluated by the VCS method during arterial occlusion test. The experimental results confirmed the correspondence between blood perfusion and blood flow velocity.

Paper Details

Date Published: 24 March 2017
PDF: 6 pages
Proc. SPIE 10336, Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII, 1033607 (24 March 2017); doi: 10.1117/12.2267955
Show Author Affiliations
M. V. Volkov, ITMO Univ. (Russian Federation)
D. A. Kostrova, ITMO Univ. (Russian Federation)
N. B. Margaryants, ITMO Univ. (Russian Federation)
I. P. Gurov, ITMO Univ. (Russian Federation)
N. P. Erofeev, St. Petersburg State Univ. (Russian Federation)
V. V. Dremin, Orel State Univ. (Russian Federation)
E. V. Zharkikh, Orel State Univ. (Russian Federation)
E. A. Zherebtsov, Orel State Univ. (Russian Federation)
I. O. Kozlov, Orel State Univ. (Russian Federation)
A. V. Dunaev, Orel State Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10336:
Saratov Fall Meeting 2016: Optical Technologies in Biophysics and Medicine XVIII
Valery V. Tuchin; Elina A. Genina; Dmitry E. Postnov; Vladimir L. Derbov, Editor(s)

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