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Proceedings Paper

Transplantation of rib cartilage reshaped with 1.56 μm laser radiation in rabbits
Author(s): E. Sobol; O. Baum; Yu. Alexandrovskaya; A. Shekhter; L. Selezneva; V. Svistuskin
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Paper Abstract

As cartilage is an ideal natural material for transplantation, its use in the ENT surgery is limited by a difficulty to get proper shape of cartilage implants. Aim of the work is to make ring-shaped cartilage implants, to check their stability after laser reshaping and to perform transplantation into rabbits in vivo. We experimented with costal cartilages of 1-2 mm in thickness obtained from 3rd and 4rd ribs of a rabbit. 1.56 μm laser (Arcuo Medical Inc.) was used for cartilage reshaping. The laser settings were established taking into account anisotropy of cartilage structure for different orientation of the implants. The reshaped cartilage implants were surgically sewn to rib cartilages of the other rabbits. The rabbits were slaughtered in 3.5-4 months after surgery. The results have shown that (1) all reshaped implants kept circular form, and (2) the implants were adhered to the native rabbit cartilage sites (3) pronounced signs of regeneration in the intermediate zones were observed. The prospects of the cartilage implants use in larynx stenosis surgery are discussed.

Paper Details

Date Published: 7 February 2017
PDF: 6 pages
Proc. SPIE 10039, Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology, 100390U (7 February 2017); doi: 10.1117/12.2266879
Show Author Affiliations
E. Sobol, Ctr. Crystallography and Photonics (Russian Federation)
O. Baum, Ctr. Crystallography and Photonics (Russian Federation)
Yu. Alexandrovskaya, Ctr. Crystallography and Photonics (Russian Federation)
A. Shekhter, Sechenov First Medical Univ. of Moscow (Russian Federation)
L. Selezneva, Sechenov First Medical Univ. of Moscow (Russian Federation)
V. Svistuskin, Sechenov First Medical Univ. of Moscow (Russian Federation)


Published in SPIE Proceedings Vol. 10039:
Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology
Brian J. F. Wong; Justus F. Ilgner; Krzysztof Izdebski, Editor(s)

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