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X-ray phase contrast imaging of biological samples using a betatron x-ray source generated in a laser wakefield accelerator
Author(s): U. Chaulagain; K. Bohacek; M. Kozlova; J. Nejdl; M. Krus; V. Horny; B. Mahieu; K. Ta-Phuoc
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Paper Abstract

In a plasma wakefield accelerator, an intense laser pulse propagates in an under-dense plasma that drives a relativistic plasma wave in which electrons can be injected and accelerated to relativistic energies within a short distance. These accelerated electrons undergo betatron oscillation and emit a collimated X-ray beam along the direction of electron velocity. This X-ray source is characterised with a source size of the order of a micrometer, a pulse duration of the order of femtosecond, and with a high spectral brightness. This novel X-ray source provides an excellent imaging tool to achieve unprecedented high-resolution image through phase contrast imaging. The phase contrast technique has the potential to reveal structures which are invisible with the conventional absorption imaging. In the X-ray phase contrast imaging, the image contrast is obtained thanks to phase shifts induced on the X-rays passing through the sample. It involves the real part of refractive index of the object. Here we present high-resolution phase contrast X-ray images of two biological samples using laser-driven Betatron X-ray source.

Paper Details

Date Published: 7 May 2017
PDF: 5 pages
Proc. SPIE 10240, Laser Acceleration of Electrons, Protons, and Ions IV, 1024014 (7 May 2017); doi: 10.1117/12.2265043
Show Author Affiliations
U. Chaulagain, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
K. Bohacek, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
Czech Technical Univ. in Prague (Czech Republic)
M. Kozlova, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
Institute of Plasma Physics of the ASCR, v.v.i. (Czech Republic)
J. Nejdl, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
Institute of Plasma Physics of the ASCR, v.v.i. (Czech Republic)
M. Krus, Institute of Plasma Physics of the ASCR, v.v.i. (Czech Republic)
V. Horny, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
Czech Technical Univ. in Prague (Czech Republic)
Institute of Plasma Physics of the ASCR, v.v.i. (Czech Republic)
B. Mahieu, Lab. d'Optique Appliquée, ENSTA, École Polytechnique, CNRS (France)
K. Ta-Phuoc, ELI Beamlines, Institute of Physics of the ASCR, v.v.i. (Czech Republic)
Lab. d'Optique Appliquée, ENSTA, École Polytechnique, CNRS (France)


Published in SPIE Proceedings Vol. 10240:
Laser Acceleration of Electrons, Protons, and Ions IV
Eric Esarey; Carl B. Schroeder; Florian J. Grüner, Editor(s)

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