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Proceedings Paper

A novel quantitative methodology for age evaluation of the human corneal endothelium
Author(s): Klervi Rannou; Gilles Thuret; Philippe Gain; Jean-Charles Pinoli; Yann Gavet
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Paper Abstract

The human corneal endothelium regulates the cornea transparency. Its cells, that cannot regenerate after birth, form a tesselated mosaic with almost perfect hexagonal cells during childhood, becoming progressively bigger and less ordered during aging. This study included 50 patients (in 10 decades groups) and 10 specular microscopy observations per patient. Five different criteria were measured on the manually segmented cells: area and perimeter of the cells as well as reduced Minkowski functionals. All these criteria were used to assess the probability of age group membership. We demonstrated that the age evaluation is near the reality, although a high variability was observed for patients between 30 and 70 years old.

Paper Details

Date Published: 14 May 2017
PDF: 8 pages
Proc. SPIE 10338, Thirteenth International Conference on Quality Control by Artificial Vision 2017, 103381D (14 May 2017); doi: 10.1117/12.2263670
Show Author Affiliations
Klervi Rannou, École des Mines de Saint-Etienne, SPIN, LGF, CNRS (France)
Gilles Thuret, Univ. Jean Monnet (France)
Ctr. Hospitalier Univ. de Saint-Étienne (France)
Institut Univ. de France (France)
Philippe Gain, Univ. Jean Monnet (France)
Ctr. Hospitalier Univ. de Saint-Étienne (France)
Jean-Charles Pinoli, École des Mines de Saint-Etienne, SPIN, LGF, CNRS (France)
Yann Gavet, École des Mines de Saint-Etienne, SPIN, LGF, CNRS (France)


Published in SPIE Proceedings Vol. 10338:
Thirteenth International Conference on Quality Control by Artificial Vision 2017
Hajime Nagahara; Kazunori Umeda; Atsushi Yamashita, Editor(s)

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