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Smart photonic materials for theranostic applications
Author(s): Do Hee Keum; Songeun Beack; Sei Kwang Hahn
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Paper Abstract

We developed melanoidin nanoparticles for in vivo noninvasive photoacoustic mapping of sentinel lymph nodes, photoacoustic tomography of gastro-intestinal tracts, and photothermal ablation cancer therapy. In addition, we developed cell-integrated poly(ethylene glycol) hydrogels for in vivo optogenetic sensing and therapy. Real-time optical readout of encapsulated heat-shock-protein-coupled fluorescent reporter cells made it possible to measure the nanotoxicity of cadmium-based quantum dots in vivo. Using optogenetic cells producing glucagon-like peptide-1, we performed lightcontrolled diabetic therapy for glucose homeostasis. Finally, we developed a smart contact lens composed of biosensors, drug delivery systems, and power sources for the treatment of diabetes as a model disease.

Paper Details

Date Published: 18 May 2017
PDF: 4 pages
Proc. SPIE 10194, Micro- and Nanotechnology Sensors, Systems, and Applications IX, 101940V (18 May 2017); doi: 10.1117/12.2262322
Show Author Affiliations
Do Hee Keum, Pohang Univ. of Science and Technology (Korea, Republic of)
Songeun Beack, Pohang Univ. of Science and Technology (Korea, Republic of)
Sei Kwang Hahn, Pohang Univ. of Science and Technology (Korea, Republic of)


Published in SPIE Proceedings Vol. 10194:
Micro- and Nanotechnology Sensors, Systems, and Applications IX
Thomas George; Achyut K. Dutta; M. Saif Islam, Editor(s)

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