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Proceedings Paper

Fluorescent diamond probes: charge sensing and intracellular delivery (Conference Presentation)
Author(s): Milos Nesladek; Michal Gulka

Paper Abstract

The talk discusses recent technological progress in fabrication of NV fluorescent nanodiamond probes for intracellular sensing. Highly luminescent nanodiamond can be fabricated, by electron or proton irradiation. This includes irradiation using liquid targets yielding high homogeneity in concentration of NV centers over the irradiation batch. The surface functionalization methods, including selective substitution of surface groups by fluorine, stabilize NV- luminescence and provide probes, sensitive to NV0 - NV- charge switching. The charge sensing, using NV0 - NV conversion is further explained and used as sensitive method for detection of charge molecules and used for real time monitoring of DNA delivery. Finally prospects for using NV diamond probes, including particles with size < 10 nm for intracellular sensing, are discussed.

Paper Details

Date Published: 2 June 2017
PDF: 1 pages
Proc. SPIE 10118, Advances in Photonics of Quantum Computing, Memory, and Communication X, 1011802 (2 June 2017); doi: 10.1117/12.2256709
Show Author Affiliations
Milos Nesladek, Univ. Hasselt (Belgium)
Michal Gulka, Univ. Hasselt (Belgium)


Published in SPIE Proceedings Vol. 10118:
Advances in Photonics of Quantum Computing, Memory, and Communication X
Zameer Ul Hasan; Philip R. Hemmer; Hwang Lee; Alan L. Migdall, Editor(s)

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