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Proceedings Paper

Combined laser-ray tracing and OCT system for biometry of the crystalline lens (Conference Presentation)
Author(s): Marco Ruggeri; Bianca M. Maceo Heilman; Yue Yao; Yu-Cherng Chang; Alex Gonzalez; Cornelis Rowaan; Ashik Mohamed; Siobhan Williams; Heather A. Durkee; Juan Silgado; Andres Bernal; Esdras Arrieta-Quintero; Arthur Ho; Jean-Marie A. Parel; Fabrice Manns
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Paper Abstract

Age-related changes in the crystalline lens shape and refractive index gradient produce changes in dioptric power and high-order aberrations that influence the optics of the whole eye and contribute to a decrease in overall visual quality. Despite their key role, the changes in lens shape and refractive index gradient with age and accommodation and their effects on high-order aberrations are still not well understood. The goal of this project was to develop a combined laser ray tracing (LRT) and optical coherence tomography (OCT) system to measure high-order aberrations, shape and refractive index gradient in non-human primate and human lenses. A miniature motorized lens stretching system was built to enable imaging and aberrometry of the lens during simulated accommodation. A positioning system was also built to enable on- and off-axis OCT imaging and aberrometry for characterization of the peripheral defocus of the lens. We demonstrated the capability of the LRT-OCT system to produce OCT images and aberration measurements of crystalline lens with age and accommodation in vitro. In future work, the information acquired with the LRT-OCT system will be used to develop an accurate age-dependent lens model to predict the role of the lens in the development of refractive error and aberrations of the whole eye.

Paper Details

Date Published: 16 May 2017
PDF: 1 pages
Proc. SPIE 10045, Ophthalmic Technologies XXVII, 100451F (16 May 2017); doi: 10.1117/12.2256235
Show Author Affiliations
Marco Ruggeri, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Bianca M. Maceo Heilman, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Yue Yao, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Yu-Cherng Chang, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Alex Gonzalez, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Cornelis Rowaan, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Ashik Mohamed, Ophthalmic Biophysics, L V Prasad Eye Institute (India)
Vision Cooperative Research Ctr., Brien Holden Vision Institute (Australia)
Siobhan Williams, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Heather A. Durkee, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Juan Silgado, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Andres Bernal, Bioniko Consulting LLC (United States)
Esdras Arrieta-Quintero, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Arthur Ho, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
Vision Cooperative Research Ctr., Brien Holden Vision Institute (Australia)
School of Optometry & Vision Science, Univ. of New South Wales (Australia)
Jean-Marie A. Parel, Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)
College of Engineering, Univ. of Miami (United States)
Vision Cooperative Research Ctr., Brien Holden Vision Institute (Australia)
Fabrice Manns, College of Engineering, Univ. of Miami (United States)
Ophthalmic Biophysics Ctr., Bascom Palmer Eye Institute (United States)


Published in SPIE Proceedings Vol. 10045:
Ophthalmic Technologies XXVII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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