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Proceedings Paper

Estimating cardiac fiber orientations in pig hearts using registered ultrasound and MR image volumes
Author(s): James D. Dormer; Yuguang Meng; Xiaodong Zhang; Rong Jiang; Mary B. Wagner; Baowei Fei
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Paper Abstract

Heart fiber mechanics can be important predictors in current and future cardiac function. Accurate knowledge of these mechanics could enable cardiologists to provide a diagnosis before conditions progress. Magnetic resonance diffusion tensor imaging (MR-DTI) has been used to determine cardiac fiber orientations. Ultrasound is capable of providing anatomical information in real time, enabling a physician to quickly adjust parameters to optimize image scans. If known fiber orientations from a template heart measured using DTI can be accurately deformed onto a cardiac ultrasound volume, fiber orientations could be estimated for the patient without the need for a costly MR scan while still providing cardiologists valuable information about the heart mechanics. In this study, we apply the method to pig hearts, which are a close representation of human heart anatomy. Experiments from pig hearts show that the registration method achieved an average Dice similarity coefficient (DSC) of 0.819 ± 0.050 between the ultrasound and deformed MR volumes and that the proposed ultrasound-based method is able to estimate the cardiac fiber orientation in pig hearts.

Paper Details

Date Published: 15 March 2017
PDF: 6 pages
Proc. SPIE 10139, Medical Imaging 2017: Ultrasonic Imaging and Tomography, 101391G (15 March 2017); doi: 10.1117/12.2255515
Show Author Affiliations
James D. Dormer, Emory Univ. (United States)
Yuguang Meng, Emory Univ. (United States)
Xiaodong Zhang, Emory Univ. (United States)
Rong Jiang, Emory Univ. (United States)
Mary B. Wagner, Emory Univ. (United States)
Baowei Fei, Emory Univ. (United States)
Georgia Institute of Technology (United States)

Published in SPIE Proceedings Vol. 10139:
Medical Imaging 2017: Ultrasonic Imaging and Tomography
Neb Duric; Brecht Heyde, Editor(s)

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