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Proceedings Paper

Optimization of real-time rigid registration motion compensation for prostate biopsies using 2D/3D ultrasound
Author(s): Derek J. Gillies; Lori Gardi; Ren Zhao; Aaron Fenster
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Paper Abstract

During image-guided prostate biopsy, needles are targeted at suspicious tissues to obtain specimens that are later examined histologically for cancer. Patient motion causes inaccuracies when using MR-transrectal ultrasound (TRUS) image fusion approaches used to augment the conventional biopsy procedure. Motion compensation using a single, user initiated correction can be performed to temporarily compensate for prostate motion, but a real-time continuous registration offers an improvement to clinical workflow by reducing user interaction and procedure time. An automatic motion compensation method, approaching the frame rate of a TRUS-guided system, has been developed for use during fusion-based prostate biopsy to improve image guidance. 2D and 3D TRUS images of a prostate phantom were registered using an intensity based algorithm utilizing normalized cross-correlation and Powell’s method for optimization with user initiated and continuous registration techniques. The user initiated correction performed with observed computation times of 78 ± 35 ms, 74 ± 28 ms, and 113 ± 49 ms for in-plane, out-of-plane, and roll motions, respectively, corresponding to errors of 0.5 ± 0.5 mm, 1.5 ± 1.4 mm, and 1.5 ± 1.6°. The continuous correction performed significantly faster (p < 0.05) than the user initiated method, with observed computation times of 31 ± 4 ms, 32 ± 4 ms, and 31 ± 6 ms for in-plane, out-of-plane, and roll motions, respectively, corresponding to errors of 0.2 ± 0.2 mm, 0.6 ± 0.5 mm, and 0.8 ± 0.4°.

Paper Details

Date Published: 3 March 2017
PDF: 8 pages
Proc. SPIE 10135, Medical Imaging 2017: Image-Guided Procedures, Robotic Interventions, and Modeling, 101351F (3 March 2017); doi: 10.1117/12.2255006
Show Author Affiliations
Derek J. Gillies, Western Univ. (Canada)
Robarts Research Institute, Western Univ. (Canada)
Lori Gardi, Western Univ. (Canada)
Robarts Research Institute, Western Univ. (Canada)
Ren Zhao, Ctr. for Imaging Technology Commercialization (Canada)
Aaron Fenster, Western Univ. (Canada)
Ctr. for Imaging Technology Commercialization (Canada)


Published in SPIE Proceedings Vol. 10135:
Medical Imaging 2017: Image-Guided Procedures, Robotic Interventions, and Modeling
Robert J. Webster; Baowei Fei, Editor(s)

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