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FADTTSter: accelerating hypothesis testing with functional analysis of diffusion tensor tract statistics
Author(s): Jean Noel; Juan C. Prieto; Martin Styner
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Paper Abstract

Functional Analysis of Diffusion Tensor Tract Statistics (FADTTS) is a toolbox for analysis of white matter (WM) fiber tracts. It allows associating diffusion properties along major WM bundles with a set of covariates of interest, such as age, diagnostic status and gender, and the structure of the variability of these WM tract properties.

However, to use this toolbox, a user must have an intermediate knowledge in scripting languages (MATLAB). FADTTSter was created to overcome this issue and make the statistical analysis accessible to any non-technical researcher. FADTTSter is actively being used by researchers at the University of North Carolina. FADTTSter guides non-technical users through a series of steps including quality control of subjects and fibers in order to setup the necessary parameters to run FADTTS.

Additionally, FADTTSter implements interactive charts for FADTTS’ outputs. This interactive chart enhances the researcher experience and facilitates the analysis of the results. FADTTSter’s motivation is to improve usability and provide a new analysis tool to the community that complements FADTTS.

Ultimately, by enabling FADTTS to a broader audience, FADTTSter seeks to accelerate hypothesis testing in neuroimaging studies involving heterogeneous clinical data and diffusion tensor imaging.

This work is submitted to the Biomedical Applications in Molecular, Structural, and Functional Imaging conference. The source code of this application is available in NITRC.

Paper Details

Date Published: 13 March 2017
PDF: 7 pages
Proc. SPIE 10137, Medical Imaging 2017: Biomedical Applications in Molecular, Structural, and Functional Imaging, 1013727 (13 March 2017); doi: 10.1117/12.2254711
Show Author Affiliations
Jean Noel, The Univ. of North Carolina at Chapel Hill (United States)
Juan C. Prieto, The Univ. of North Carolina at Chapel Hill (United States)
Martin Styner, The Univ. of North Carolina at Chapel Hill (United States)


Published in SPIE Proceedings Vol. 10137:
Medical Imaging 2017: Biomedical Applications in Molecular, Structural, and Functional Imaging
Andrzej Krol; Barjor Gimi, Editor(s)

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