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3D frequency-domain ultrasound waveform tomography breast imaging
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Paper Abstract

Frequency-domain ultrasound waveform tomography is a promising method for the visualization and characterization of breast disease. It has previously been shown to accurately reconstruct the sound speed distributions of breasts of varying densities. The reconstructed images show detailed morphological and quantitative information that can help differentiate different types of breast disease including benign and malignant lesions. The attenuation properties of an ex vivo phantom have also been assessed. However, the reconstruction algorithms assumed a 2D geometry while the actual data acquisition process was not. Although clinically useful sound speed images can be reconstructed assuming this mismatched geometry, artifacts from the reconstruction process exist within the reconstructed images. This is especially true for registration across different modalities and when the 2D assumption is violated. For example, this happens when a patient’s breast is rapidly sloping. It is also true for attenuation imaging where energy lost or gained out of the plane gets transformed into artifacts within the image space. In this paper, we will briefly review ultrasound waveform tomography techniques, give motivation for pursuing the 3D method, discuss the 3D reconstruction algorithm, present the results of 3D forward modeling, show the mismatch that is induced by the violation of 3D modeling via numerical simulations, and present a 3D inversion of a numerical phantom.

Paper Details

Date Published: 13 March 2017
PDF: 14 pages
Proc. SPIE 10139, Medical Imaging 2017: Ultrasonic Imaging and Tomography, 1013909 (13 March 2017); doi: 10.1117/12.2254399
Show Author Affiliations
Gursharan Yash Sandhu, Delphinus Medical Technologies, Inc. (United States)
Erik West, Delphinus Medical Technologies, Inc. (United States)
Cuiping Li, Delphinus Medical Technologies, Inc. (United States)
Karmanos Cancer Institute (United States)
Olivier Roy, Delphinus Medical Technologies, Inc. (United States)
Karmanos Cancer Institute (United States)
Neb Duric, Delphinus Medical Technologies, Inc. (United States)
Karmanos Cancer Institute (United States)


Published in SPIE Proceedings Vol. 10139:
Medical Imaging 2017: Ultrasonic Imaging and Tomography
Neb Duric; Brecht Heyde, Editor(s)

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