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Proceedings Paper

Nonrigid registration of 3D longitudinal optical coherence tomography volumes with choroidal neovascularization
Author(s): Qiangding Wei; Fei Shi; Weifang Zhu; Dehui Xiang; Haoyu Chen; Xinjian Chen
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Paper Abstract

In this paper, we propose a 3D registration method for retinal optical coherence tomography (OCT) volumes. The proposed method consists of five main steps: First, a projection image of the 3D OCT scan is created. Second, the vessel enhancement filter is applied on the projection image to detect vessel shadow. Third, landmark points are extracted based on both vessel positions and layer information. Fourth, the coherent point drift method is used to align retinal OCT volumes. Finally, a nonrigid B-spline-based registration method is applied to find the optimal transform to match the data. We applied this registration method on 15 3D OCT scans of patients with Choroidal Neovascularization (CNV). The Dice coefficients (DSC) between layers are greatly improved after applying the nonrigid registration.

Paper Details

Date Published: 24 February 2017
PDF: 8 pages
Proc. SPIE 10133, Medical Imaging 2017: Image Processing, 101330X (24 February 2017); doi: 10.1117/12.2253999
Show Author Affiliations
Qiangding Wei, Soochow Univ. (China)
Fei Shi, Soochow Univ. (China)
Weifang Zhu, Soochow Univ. (China)
Dehui Xiang, Soochow Univ. (China)
Haoyu Chen, Shantou Univ. (China)
Chinese Univ. of Hong Kong (China)
Xinjian Chen, Soochow Univ. (China)


Published in SPIE Proceedings Vol. 10133:
Medical Imaging 2017: Image Processing
Martin A. Styner; Elsa D. Angelini, Editor(s)

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