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Proceedings Paper

Simultaneous and co-localized acousto-optic measurements of spectral and temporal properties of diffusive media
Author(s): Michal Balberg; Revital Shechter; Pinhas Girshovitz; Ilan Breskin; Sergio Fantini
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Paper Abstract

Acousto-optic (AO) modulation of light is used to extract both temporal and spectral information of diffusive media such as biological tissue, where they provide measures of blood flow and oxygen saturation of hemoglobin, respectively. The temporal information is extracted from the width of the power spectrum of the light intensity, whereas the spectral information is calculated from the spatial decay of the cross correlation between the light intensity and the generated ultrasonic signal. The ultrasonic signal is a coded phase modulated signal with a narrow autocorrelation, enabling localization of the measurement volume. Two different liquid phantoms are used, with similar scattering but different absorption properties. The difference in absorption calculated with the AO signal is compared to calculations based on the modified Beer Lambert law. As the same AO signal is used to extract both modalities, it might be used to extract hemodynamic related changes in the brain for diagnostic and functional assessment.

Paper Details

Date Published: 24 March 2017
PDF: 7 pages
Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 1005903 (24 March 2017); doi: 10.1117/12.2253848
Show Author Affiliations
Michal Balberg, Holon Institute of Technology (Israel)
Revital Shechter, Ornim Medical Ltd. (Israel)
Pinhas Girshovitz, Tel Aviv Univ. (Israel)
Ilan Breskin, Ornim Medical Ltd. (Israel)
Sergio Fantini, Tufts Univ. (United States)

Published in SPIE Proceedings Vol. 10059:
Optical Tomography and Spectroscopy of Tissue XII
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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