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Proceedings Paper

Frequency domain non-contact photoacoustic microscopy
Author(s): Deepu George; Harriet Lloyd; Ronald H. Silverman; Parag V. Chitnis
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Paper Abstract

We present a non-contact “frequency domain photoacoustic microscope” (Fd-PAM) in which photoacoustic signal is generated by an amplitude modulated continuous-wave (CW) laser and detected at the sample surface using two wave mixing (interferometer) in a photorefractive crystal (PRC). The optical detection eliminates the need for a coupling medium, thus making the probe contactless and mitigates loss in signal-to-noise ratio (SNR) resulting from attenuation associated with wave propagation from the sample to the sensor. The single frequency excitation enables the use of extremely narrow band detection techniques like a lock-in amplifier for noise suppression. Our approach also can image multi-layered specimen and directly produce an image that is equivalent to the maximum-intensity projection of the 3D image volume.

Paper Details

Date Published: 3 March 2017
PDF: 7 pages
Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 1006443 (3 March 2017); doi: 10.1117/12.2253665
Show Author Affiliations
Deepu George, George Mason Univ. (United States)
Harriet Lloyd, Edward S. Harkness Eye Institute, Columbia Univ. (United States)
Ronald H. Silverman, Edward S. Harkness Eye Institute, Columbia Univ. (United States)
Parag V. Chitnis, George Mason Univ. (United States)

Published in SPIE Proceedings Vol. 10064:
Photons Plus Ultrasound: Imaging and Sensing 2017
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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