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Proceedings Paper

Towards a clinical implementation of uOCT instrument for in vivo imaging of human airways
Author(s): Hui Min Leung; Dongyao Cui; Timothy N. Ford; Daryl Hyun; Jing Dong; Biwei Yin; Susan E. Birket; George M. Solomon; Linbo Liu; Steven M. Rowe; Guillermo J. Tearney
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Paper Abstract

High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways.

Paper Details

Date Published: 20 April 2017
PDF: 1 pages
Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 1005614 (20 April 2017); doi: 10.1117/12.2253423
Show Author Affiliations
Hui Min Leung, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)
Dongyao Cui, Nanyang Technological Univ. (Singapore)
Timothy N. Ford, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)
Daryl Hyun, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)
Jing Dong, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)
Biwei Yin, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)
Susan E. Birket, Univ. of Alabama at Birmingham (United States)
George M. Solomon, Univ. of Alabama at Birmingham (United States)
Linbo Liu, Nanyang Technological Univ. (Singapore)
Steven M. Rowe, Univ. of Alabama at Birmingham (United States)
Guillermo J. Tearney, Harvard Medical School (United States)
Wellman Ctr. for Photomedicine (United States)
Massachusetts General Hospital (United States)


Published in SPIE Proceedings Vol. 10056:
Design and Quality for Biomedical Technologies X
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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