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Proceedings Paper

Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope
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Paper Abstract

Initial feasibility of a spatial frequency domain imaging system was studied consisting of a hand held miniaturized projector and a rigid endoscope. Three wavelengths and two spatial frequencies were used for imaging. The system was calibrated using tissue mimicking phantoms. In vivo imaging was performed on five live mouse tumor models, and the absorption, scattering, hemoglobin oxygen saturation was measured. The initial promising results indicate that the spatial frequency domain imaging can a very useful tool for quantitative wide field tissue evaluation during minimally invasive image guided surgery.

Paper Details

Date Published: 27 March 2017
PDF: 5 pages
Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591S (27 March 2017); doi: 10.1117/12.2253221
Show Author Affiliations
Sreyankar Nandy, Washington Univ. in St. Louis (United States)
Mohsen Erfanzadeh, Univ. of Connecticut (United States)
Feifei Zhou, Univ. of Connecticut (United States)
Quing Zhu, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 10059:
Optical Tomography and Spectroscopy of Tissue XII
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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