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Proceedings Paper

Non-interferometric deep optical resolution photoacoustic remote sensing microscopy (Conference Presentation)

Paper Abstract

A novel all-optical non-contact photoacoustic microscopy system is introduced. The confocal configuration is used to ensure detection of initial pressure shock wave-induced intensity reflections at the subsurface origin where pressures are largest. Phantom studies confirm signal dependence on optical absorption, index-contrast, and excitation fluence. Taking advantage of a focused1310 nm interrogation beam, the penetration depth of the system is improved to ~ 2mm for an optical resolution system. High signal-to-noise ratios (>60dB) with ~ 2.5 cm working distance from the objective lens to the sample is achieved. Real-time in-vivo imaging of microvasculature and melanoma tumors are demonstrated.

Paper Details

Date Published: 24 April 2017
PDF: 1 pages
Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 1006420 (24 April 2017); doi: 10.1117/12.2252972
Show Author Affiliations
Parsin H. HajiReza, Univ. of Alberta (Canada)
illumiSonics Inc. (Canada)
Kevan L. Bell, Univ. of Alberta (Canada)
Wei Shi, Univ. of Alberta (Canada)
Roger J. Zemp, Univ. of Alberta (Canada)
illumiSonics Inc. (Canada)

Published in SPIE Proceedings Vol. 10064:
Photons Plus Ultrasound: Imaging and Sensing 2017
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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