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Proceedings Paper

Design verification of a compact system for detecting tissue perfusion using bimodal diffuse optical technologies
Author(s): Julia M. Pakela; Taylor L. Hedrick; Seung Yup Lee; Karthik Vishwanath; Sara Zanfardino; Yooree G. Chung; Michael C. Helton; Noah J. Kolodziejski; Christopher J. Stapels; Daniel R. McAdams; Daniel E. Fernandez; James F. Christian; Stephen E. Feinberg; Mary-Ann Mycek
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Paper Abstract

It is essential to monitor tissue perfusion during and after reconstructive surgery, as restricted blood flow can result in graft failures. Current clinical procedures are insufficient to monitor tissue perfusion, as they are intermittent and often subjective. To address this unmet clinical need, a compact, low-cost, multimodal diffuse correlation spectroscopy and diffuse reflectance spectroscopy system was developed. We verified system performance via tissue phantoms and experimental protocols for rigorous bench testing. Quantitative data analysis methods were employed and tested to enable the extraction of tissue perfusion parameters. This design verification study assures data integrity in future in vivo studies.

Paper Details

Date Published: 17 February 2017
PDF: 7 pages
Proc. SPIE 10072, Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics, 1007217 (17 February 2017); doi: 10.1117/12.2252811
Show Author Affiliations
Julia M. Pakela, Univ. of Michigan (United States)
Taylor L. Hedrick, Univ. of Michigan (United States)
Seung Yup Lee, Univ. of Michigan (United States)
Karthik Vishwanath, Miami Univ. (United States)
Sara Zanfardino, Miami Univ. (United States)
Yooree G. Chung, Univ. of Michigan (United States)
Michael C. Helton, Univ. of Michigan (United States)
Noah J. Kolodziejski, Radiation Monitoring Devices, Inc. (United States)
Christopher J. Stapels, Radiation Monitoring Devices, Inc. (United States)
Daniel R. McAdams, Radiation Monitoring Devices, Inc. (United States)
Daniel E. Fernandez, Radiation Monitoring Devices, Inc. (United States)
James F. Christian, Radiation Monitoring Devices, Inc. (United States)
Stephen E. Feinberg, Univ. of Michigan (United States)
Mary-Ann Mycek, Univ. of Michigan (United States)


Published in SPIE Proceedings Vol. 10072:
Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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