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Proceedings Paper

Light activated microbubbles for imaging and microsurgery
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Paper Abstract

Imaging and microsurgery procedures based on the photoacoustic effect have recently attracted much attention for cancer treatment. Light absorption in the nanosecond regime triggers thermoelastic processes that induce ultrasound emission and even cavitation. The ultrasound waves may be detected to reconstruct images, while cavitation may be exploited to kill malignant cells. The potential of gold nanorods as contrast agents for photoacoustic imaging has been extensively investigated, but still little is known about their use to trigger cavitation. Here, we investigated the influence of environment thermal properties on the ability of gold nanorods to trigger cavitation by probing the photoacoustic emission as a function of the excitation fluence. We are confident that these results will provide useful directions to the development of new strategies for therapies based on the photoacoustic effect.

Paper Details

Date Published: 3 March 2017
PDF: 7 pages
Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 1006457 (3 March 2017); doi: 10.1117/12.2252783
Show Author Affiliations
Lucia Cavigli, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Filippo Micheletti, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Paolo Tortoli, Univ. degli Studi di Firenze (Italy)
Sonia Centi, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Sarah Lai, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Claudia Borri, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Francesca Rossi, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Fulvio Ratto, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)
Roberto Pini, Istituto di Fisica Applicata "Nello Carrara", CNR (Italy)


Published in SPIE Proceedings Vol. 10064:
Photons Plus Ultrasound: Imaging and Sensing 2017
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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