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Proceedings Paper

Improving visibility in limited-view scenarios with dynamic particle-enhanced optoacoustic tomography
Author(s): X. Luís Deán-Ben; Lu Ding; Daniel Razansky
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Paper Abstract

Limited-view artefacts affect most optoacoustic (photoacoustic) imaging systems due to geometrical constraints that impede achieving full tomographic coverage as well as limited light penetration into scattering and absorbing objects. Indeed, it has been theoretically established and experimentally verified that accurate optoacoustic images can only be obtained if the imaged sample is fully enclosed (< π angular coverage) by the measuring locations. Since in many cases full angular coverage cannot be achieved, the visibility of structures along certain orientations is hampered. These effects are of particular relevance in the case of hand-held scanners with the imaged volume only accessible from one side. Herein, a new approach termed dynamic particle-enhanced optoacoustic tomography (DPOT) is described for accurate structural imaging in limited-view scenarios. The method is based on the non-linear combination of a sequence of tomographic reconstructions representing sparsely distributed moving particles. Good performance of the method is demonstrated in experiments consisting of dynamic visualization of flow of suspended microspheres in three-dimensions. The method is expected to be applicable for improving accuracy of angiographic optoacoustic imaging in living organisms.

Paper Details

Date Published: 3 March 2017
PDF: 6 pages
Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100641I (3 March 2017); doi: 10.1117/12.2252621
Show Author Affiliations
X. Luís Deán-Ben, Institute for Biological and Medical Imaging, Helmholtz Ctr. Munich (Germany)
Technical Univ. of Munich (Germany)
Lu Ding, Institute for Biological and Medical Imaging, Helmholtz Ctr. Munich (Germany)
Technical Univ. of Munich (Germany)
Daniel Razansky, Institute for Biological and Medical Imaging, Helmholtz Ctr. Munich (Germany)
School of Medicine, Technical Univ. of Munich (Germany)


Published in SPIE Proceedings Vol. 10064:
Photons Plus Ultrasound: Imaging and Sensing 2017
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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