Share Email Print
cover

Proceedings Paper

Considerations for ex vivo thermal tissue testing exemplified using the fresh porcine longissimus muscle model for endometrial ablation
Author(s): James H. Fugett; Haydon E. Bennett; Joshua L. Shrout; James E. Coad
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Expansions in minimally invasive medical devices and technologies with thermal mechanisms of action are continuing to advance the practice of medicine. These expansions have led to an increasing need for appropriate animal models to validate and quantify device performance. The planning of these studies should take into consideration a variety of parameters, including the appropriate animal model (test system - ex vivo or in vivo; species; tissue type), treatment conditions (test conditions), predicate device selection (as appropriate, control article), study timing (Day 0 acute to more than Day 90 chronic survival studies), and methods of tissue analysis (tissue dissection - staining methods). These considerations are discussed and illustrated using the fresh extirpated porcine longissimus muscle model for endometrial ablation.

Paper Details

Date Published: 22 February 2017
PDF: 11 pages
Proc. SPIE 10066, Energy-based Treatment of Tissue and Assessment IX, 100660L (22 February 2017); doi: 10.1117/12.2252308
Show Author Affiliations
James H. Fugett, West Virginia Univ. Health Sciences Ctr. (United States)
Haydon E. Bennett, West Virginia Univ. Health Sciences Ctr. (United States)
Joshua L. Shrout, West Virginia Univ. Health Sciences Ctr. (United States)
James E. Coad, West Virginia Univ. Health Sciences Ctr. (United States)


Published in SPIE Proceedings Vol. 10066:
Energy-based Treatment of Tissue and Assessment IX
Thomas P. Ryan, Editor(s)

© SPIE. Terms of Use
Back to Top