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Proceedings Paper

Imaging small animal whole-body dynamics by single-impulse panoramic photoacoustic computed tomography
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Paper Abstract

Imaging of small animals, especially rodents provides physiological, pathological, and phenotypical insights into the most relevant milieu—an intact, living system. Currently, non-optical small-animal wholebody imaging approaches lack either spatiotemporal resolution or functional contrasts, whereas pure optical imaging suffers from either shallow penetration (up to ~1 mm) or a poor resolution-to-depth ratio (~1/3). Here, we present a standalone system that breaks all the above limitations. Our system features high spatiotemporal resolution and deep penetration, and can capture anatomical and functional contrasts. We imaged mouse wholebody dynamics in real time with clear sub-organ anatomical and functional details.

Paper Details

Date Published: 23 March 2017
PDF: 6 pages
Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100640M (23 March 2017); doi: 10.1117/12.2251593
Show Author Affiliations
Lei Li, California Institute of Technology (United States)
Liren Zhu, California Institute of Technology (United States)
Washington Univ. in St. Louis (United States)
Cheng Ma, Tsinghua Univ. (China)
Li Lin, California Institute of Technology (United States)
Washington Univ. in St. Louis (United States)
Junjie Yao, Duke Univ. (United States)
Lidai Wang, City Univ. of Hong Kong (China)
Konstantin Maslov, California Institute of Technology (United States)
Ruiying Zhang, Washington Univ. in St. Louis (United States)
Wanyi Chen, Washington Univ. in St. Louis (United States)
Junhui Shi, California Institute of Technology (United States)
Lihong V. Wang, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 10064:
Photons Plus Ultrasound: Imaging and Sensing 2017
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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