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Proceedings Paper

In vivo monitoring laser tissue interaction using high resolution Fourier-domain optical coherence tomography
Author(s): Hang Chan Jo; Dong Jun Shin; Jin-Chul Ahn; Phil-Sang Chung; DaeYu Kim
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Paper Abstract

Laser-induced therapies include laser ablation to remove or cut target tissue by irradiating high-power focused laser beam. These laser treatments are widely used tools for minimally invasive surgery and retinal surgical procedures in clinical settings. In this study, we demonstrate laser tissue interaction images of various sample tissues using high resolution Fourier-domain optical coherence tomography (Fd-OCT). We use a Q-switch diode-pumped Nd:YVO4 nanosecond laser (532nm central wavelength) with a 4W maximum output power at a 20 kHz repetition rate to ablate in vitro and in vivo samples including chicken breast and mouse ear tissues. The Fd-OCT system acquires time-series Bscan images at the same location during the tissue ablation experiments with 532nm laser irradiation. The real-time series of OCT cross-sectional (B-scan) images compare structural changes of 532nm laser ablation using same and different laser output powers. Laser tissue ablation is demonstrated by the width and the depth of the tissue ablation from the B-scan images.

Paper Details

Date Published: 15 February 2017
PDF: 6 pages
Proc. SPIE 10062, Optical Interactions with Tissue and Cells XXVIII, 1006217 (15 February 2017); doi: 10.1117/12.2251558
Show Author Affiliations
Hang Chan Jo, Dankook Univ. (Korea, Republic of)
Dong Jun Shin, Dankook Univ. (Korea, Republic of)
Jin-Chul Ahn, Beckman Laser Institute Korea, Dankook Univ. (Korea, Republic of)
Phil-Sang Chung, Beckman Laser Institute Korea, Dankook Univ. (Korea, Republic of)
DaeYu Kim, Beckman Laser Institute Korea, Dankook Univ. (Korea, Republic of)


Published in SPIE Proceedings Vol. 10062:
Optical Interactions with Tissue and Cells XXVIII
E. Duco Jansen; Hope Thomas Beier, Editor(s)

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