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Proceedings Paper

Optical focusing through biological tissue and tissue-mimicking phantoms up to 9.6 centimeters thick with digital optical phase conjugation
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Paper Abstract

Optical phase conjugation (OPC) based wavefront shaping techniques focus light through or within scattering media, which is critically important for deep-tissue optical imaging, manipulation, and therapy. However, to date, the sample thicknesses used in wavefront shaping experiments have been limited to only a few millimeters or several transport mean free paths. Here, by using a long-coherence-length laser and an optimized digital OPC system that efficiently delivers light power, we focused 532 nm light through tissue-mimicking phantoms up to 9.6 cm thick, as well as through ex vivo chicken breast tissue up to 2.5 cm thick.

Paper Details

Date Published: 21 February 2017
PDF: 6 pages
Proc. SPIE 10073, Adaptive Optics and Wavefront Control for Biological Systems III, 100730G (21 February 2017); doi: 10.1117/12.2251052
Show Author Affiliations
Yuecheng Shen, California Institute of Technology (United States)
Washington Univ. in St. Louis (United States)
Yan Liu, California Institute of Technology (United States)
Washington Univ. in St. Louis (United States)
Cheng Ma, Washington Univ. in St. Louis (United States)
Lihong V. Wang, California Institute of Technology (United States)
Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 10073:
Adaptive Optics and Wavefront Control for Biological Systems III
Thomas G. Bifano; Joel Kubby; Sylvain Gigan, Editor(s)

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