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Proceedings Paper

Transcutaneous measurement of glomerular filtration rate in conscious laboratory animals: state of the art and future perspectives
Author(s): Jochen Friedemann; Daniel Schock-Kusch; Yury Shulhevich
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Paper Abstract

Transcutaneous measurement of Glomerular Filtration Rate (tGFR) is now frequently used in preclinical in vivo animal studies. tGFR allows consecutive measurements on the same animal, including multiple measurements on a daily basis. A description of the measurement device and its many applications, along with examples from the recent literature will be given. We will highlight the fields of interest in which the system is used and give an overview about its performance versus endogenous and other exogenous methods of GFR measurement. A special focus will be put on the precision of tGFR compared to standard measurements employed in the research setting.

Paper Details

Date Published: 21 February 2017
PDF: 9 pages
Proc. SPIE 10079, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications IX, 100790J (21 February 2017); doi: 10.1117/12.2250887
Show Author Affiliations
Jochen Friedemann, MediBeacon GmbH (Germany)
Daniel Schock-Kusch, MediBeacon GmbH (Germany)
Yury Shulhevich, MediBeacon GmbH (Germany)


Published in SPIE Proceedings Vol. 10079:
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications IX
Samuel Achilefu; Ramesh Raghavachari, Editor(s)

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