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Proceedings Paper

Design and fabrication of solid phantoms for NIR water fraction studies
Author(s): Gordon T. Kennedy; Griffin R. Lentsch; Brandon Trieu; Adrien Ponticorvo; Rolf B. Saager; Anthony J. Durkin
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Paper Abstract

Tissue simulating phantoms provide a valuable platform for quantitative evaluation of the performance of diffuse optical devices. In this paper we report the development of a poly(dimethylsiloxane) (PDMS) tissue phantom that mimics the spectral characteristics of tissue water. We have developed these phantoms to mimic different water fractions in tissue for testing new devices within the context of clinical applications such as burn wound triage. Compared to liquid phantoms, PDMS phantoms are easier to transport and use, and have a longer usable life than gelatin based phantoms. The pthalocyanine dye 9606 was used to provide an absorption feature of in the vicinity of 970 nm. Scattering properties were independently determined by adding titanium dioxide powder to obtain reduced scattering coefficients similar to that of tissue in the near infrared. Phantom properties were characterized using the techniques of inverse adding doubling and spatial frequency domain imaging. Results presented here demonstrate that we can fabricate solid phantoms that can be used to simulate different water fractions.

Paper Details

Date Published: 14 March 2017
PDF: 6 pages
Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560A (14 March 2017); doi: 10.1117/12.2250672
Show Author Affiliations
Gordon T. Kennedy, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Griffin R. Lentsch, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Brandon Trieu, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Adrien Ponticorvo, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Rolf B. Saager, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)
Anthony J. Durkin, Beckman Laser Institute and Medical Clinic (United States)
Univ. of California, Irvine (United States)


Published in SPIE Proceedings Vol. 10056:
Design and Quality for Biomedical Technologies X
Ramesh Raghavachari; Rongguang Liang, Editor(s)

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