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Proceedings Paper

Breast cancer detection using Ktrans MRI imaging to guide near infrared spectroscopy tomography
Author(s): Jinchao Feng; Shudong Jiang; Junqing Xu; Yan Zhao; Jiang Gui; Brian W. Pogue; Keith D. Paulsen
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Paper Abstract

The parametric image of Volume Transfer Coefficient (Ktrans) in MRI has been used to guide image reconstruction of Near-Infrared Spectral Tomography (NIRST). The image reconstruction used direct regularization, in which no segmentation has been involved. A total of 24 patients were involved in this study and the reconstructed results show that the tumor total hemoglobin (HbT) contrast could be used to differentiate the malignant from the benign cases (p-value= 0.018). The addition of the MRI information allows more accurate and definitive HbT values from the NIRST.

Paper Details

Date Published: 18 February 2017
PDF: 8 pages
Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100590O (18 February 2017); doi: 10.1117/12.2250649
Show Author Affiliations
Jinchao Feng, Dartmouth College (United States)
Beijing Univ. of Technology (China)
Shudong Jiang, Dartmouth College (United States)
Junqing Xu, Dartmouth College (United States)
Xijing Hospital (China)
Yan Zhao, Dartmouth College (United States)
Jiang Gui, Geisel School of Medicine, Dartmouth College (United States)
Brian W. Pogue, Dartmouth College (United States)
Keith D. Paulsen, Dartmouth College (United States)


Published in SPIE Proceedings Vol. 10059:
Optical Tomography and Spectroscopy of Tissue XII
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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