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Proceedings Paper

False dyssynchrony: problem with image-based cardiac functional analysis using x-ray computed tomography
Author(s): Masafumi Kidoh; Zeyang Shen; Yuki Suzuki; Luisa Ciuffo; Hiroshi Ashikaga; George S. K. Fung; Yoshito Otake; Stefan L. Zimmerman; Joao A. C. Lima; Takahiro Higuchi; Okkyun Lee; Yoshinobu Sato; Lewis C. Becker; Elliot K. Fishman; Katsuyuki Taguchi
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Paper Abstract

We have developed a digitally synthesized patient which we call “Zach” (Zero millisecond Adjustable Clinical Heart) phantom, which allows for an access to the ground truth and assessment of image-based cardiac functional analysis (CFA) using CT images with clinically realistic settings. The study using Zach phantom revealed a major problem with image-based CFA: "False dyssynchrony." Even though the true motion of wall segments is in synchrony, it may appear to be dyssynchrony with the reconstructed cardiac CT images. It is attributed to how cardiac images are reconstructed and how wall locations are updated over cardiac phases. The presence and the degree of false dyssynchrony may vary from scan-to-scan, which could degrade the accuracy and the repeatability (or precision) of image-based CT-CFA exams.

Paper Details

Date Published: 9 March 2017
PDF: 7 pages
Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101321U (9 March 2017); doi: 10.1117/12.2250257
Show Author Affiliations
Masafumi Kidoh, Johns Hopkins Univ. School of Medicine (United States)
Zeyang Shen, Johns Hopkins Univ. School of Medicine (United States)
Southeast Univ. (China)
Yuki Suzuki, Johns Hopkins Univ. School of Medicine (United States)
Osaka Univ. (Japan)
Nara Advanced Institute of Science and Technology (Japan)
Luisa Ciuffo, Johns Hopkins Univ. School of Medicine (United States)
Hiroshi Ashikaga, Johns Hopkins Univ. School of Medicine (United States)
George S. K. Fung, Johns Hopkins Univ. School of Medicine (United States)
Yoshito Otake, Nara Advanced Institute of Science and Technology (Japan)
Stefan L. Zimmerman, Johns Hopkins Univ. School of Medicine (United States)
Joao A. C. Lima, Johns Hopkins Univ. School of Medicine (United States)
Takahiro Higuchi, Julius-Maximilians-Univ. Würzburg (Germany)
Okkyun Lee, Johns Hopkins Univ. School of Medicine (United States)
Yoshinobu Sato, Nara Advanced Institute of Science and Technology (Japan)
Lewis C. Becker, Johns Hopkins Univ. School of Medicine (United States)
Elliot K. Fishman, Johns Hopkins Univ. School of Medicine (United States)
Katsuyuki Taguchi, Johns Hopkins Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 10132:
Medical Imaging 2017: Physics of Medical Imaging
Thomas G. Flohr; Joseph Y. Lo; Taly Gilat Schmidt, Editor(s)

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